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Set 13 Cardiac Muscle

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Question 1

(Multiple Choice)

Free
Cardiac muscle cells in the atria are capable of contracting spontaneously because of a spontaneous depolarization that results from:

A)An inward current through a hyperpolarization-activated channel.
B)Cyclic changes in the activity of Na+,K+-ATPase.
C)Slow leak of Ca++ through the dihydropyridine receptor.
D)Cyclic changes in the activity of the sarcolemmal Ca++ pump.
E)Cyclic changes in the activity of SERCA.

Answer

Question 2

(Multiple Choice)

Free
Calsequestrin in cardiac muscle:

A)Acts as a high-affinity Ca++ buffer in the cytosol.
B)Acts as a low-affinity Ca++ buffer in the SR lumen,near the ryanodine receptor.
C)Promotes Ca++ accumulation by the mitochondria.
D)Increases the Ca++ affinity of the sarcolemmal Ca++ pump.
E)Facilitates myosin binding to the actin thin filament.

Answer

Question 3

(Multiple Choice)

Free
Relaxation of cardiac muscle typically requires:

A)Myosin light-chain dephosphorylation.
B)Activation of the ryanodine receptor.
C)Ca++ uptake by the sarcoplasmic reticulum (SR).
D)Phosphorylation of phospholamban.
E)Activation of the dihydropyridine receptor.

Answer