Course
Cell Biology
Study Pack
Set 12 Intracellular Compartments And Protein Sorting
Question 1
(Multiple Choice)
Free
In the following schematic diagram of a nuclear pore complex, on which side is the cytosol located? What is the approximate diameter of the pore, as indicated by the vertical bar? 
A) Right; 1 µm
B) Right; 0.1 µm
C) Left; 1 µm
D) Left; 0.1 µm
Answer
Question 2
(Multiple Choice)
Free
Imagine a protein that has been engineered to contain a nuclear localization signal, a nuclear export signal, a C-terminal peroxisomal targeting sequence, and a canonical endoplasmic reticulum (ER) signal sequence. With all of these signals, where would you expect to find the protein after its synthesis?
A) Cytosol
B) Nucleus
C) Shuttling between the cytosol and the nucleus
D) Peroxisomes
E) Endoplasmic reticulum
Answer
Question 3
(Multiple Choice)
Free
Which of the following scenarios does NOT normally occur on a nuclear pore complex?
A) A protein complex is imported into the nucleus, with ONLY one of its subunits containing a nuclear localization signal (NLS).
B) In a single pore, an NLS-containing protein is imported, while at the same time a nuclear export signal (NES)-containing protein is exported.
C) A nuclear import receptor is exported from the nucleus through the pore.
D) A protein is imported on its own through the pore, without the need for a separate import receptor.
E) All of the above are possible scenarios and occur naturally.
Answer