Course

Genetics

Study Pack

Set 5 Growth Factorsreceptorsand Cancer

Back to Sets
Question 1

(Multiple Choice)

Free
Overexpression of growth receptors helps to promote cancer growth by

A)Stimulating the dimerization and transphosphorylation of the receptors.
B)Turning off downstream signaling.
C)Promoting mitogenic signaling.
D)A and C.
E)None of the above.

Answer

Question 2

(Multiple Choice)

Free
Which of the following is NOT true of the Src protein?

A)Src operates as a protein kinase.
B)Src phosphorylates ADP to make ATP.
C)Src can serve as a kinase substrate.
D)A and C.
E)None of the above.

Answer

Question 3

(Multiple Choice)

Free
Which of the following statements is FALSE regarding Ras mutations in cancer patients?

A)Mutations often occur at codons 12,13,or 61.
B)Oncogenic mutations usually result in higher levels of GDP-bound Ras.
C)Oncogenic mutations usually result in higher levels of GTP-bound Ras.
D)Cells often have compromised activity of GTPase-activating proteins GAPs).
E)None of the above.

Answer