Course

Genetics

Study Pack

Set 10 Eternal Life Cell Immortalization And Tumorigenesis

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Question 1

(Multiple Choice)

Free
Some cancer cells escape crisis by

A)Overexpressing hTERT.
B)Activating the ALT mechanism.
C)Shortening their telomeres.
D)A and B.
E)None of the above.

Answer

Question 2

(Multiple Choice)

Free
Why does loss of telomerase activity in humans lead to severe phenotypes in the first generation,while loss of telomerase activity in laboratory mice takes several generations to exhibit any sort of phenotype?

A)Mouse cells have shorter telomeres.
B)Human cells have shorter telomeres.
C)Mouse cells express higher levels of hTERT.
D)Human cells express higher levels of hTERT.
E)The length of mouse telomeres does not change over time.

Answer

Question 3

(Multiple Choice)

Free
In normal cells,the telomeric DNA sequences

A)Get shorter with successive cell generations.
B)Get longer with successive cell generations.
C)Remain unchanged throughout successive cell generations.
D)Disappear after the first generation of daughter cells.
E)None of the above.

Answer