Activation of Myc may result in all of the following EXCEPT
A)Hyperphosphorylation of pRb. B)Increased expression of CDK4. C)Degradation of p27Kip1. D)Increased transcription of target genes by E2F transcription factors. E)Decreased activation of cyclin E/CDK2 complexes.
An increase in cyclin D activity may result from all of the following EXCEPT
A)Activation of the Ras signaling pathway. B)Activation of the Hedgehog signaling pathway. C)An increase in NF-κB expression. D)A decrease in STAT expression. E)A decrease in p16INK4A expression.
A)Promote initiation of transcription. B)Complex with hyperphosphorylated pRb. C)Repress E2F family activity. D)Add acetyl groups to E2F promoters. E)Promote initiation of translation.