Course

Microbiology

Study Pack

Set 36 Antiviral Chemotherapy

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Question 1

(Multiple Choice)

Free
How does the antiviral drug amantadine inhibit the replication of influenza?

A) It binds to the M2 ion channel and blocks the uncoating of the RNPs.
B) It binds to sialic acid on the host cell and prevents binding of the virion.
C) It binds to the HA protein on the virion and prevents binding to the host cell.
D) It binds to the polymerase protein and halts genome replication.
E) It binds to the nucleocapsid protein and prevents packaging of the viral RNA.

Answer

Question 2

(Multiple Choice)

Free
Which of the following describes how the nonnucleoside inhibitors of the HIV reverse transcriptase are different than the nucleoside inhibitors?

A) The nonnucleoside inhibitors prevent addition of the next nucleotide.
B) The nonnucleoside inhibitors do not bind to the active site of the enzyme.
C) The nonnucleoside inhibitors must be activated by the cellular thymidine kinase.
D) The nonnucleoside inhibitors prevent synthesis of the reverse transcriptase.
E) The nonnucleoside inhibitors lack a 3' OH group.

Answer

Question 3

(Multiple Choice)

Free
Many antiviral drugs, like AZT and acyclovir, belong to which of the following groups of compounds?

A) Nucleotide analogues
B) Nucleoside analogues
C) Nonnucleoside inhibitors
D) Neuraminidase inhibitors
E) Protease inhibitors

Answer