Question 2

(Multiple Choice)

Which of the following describes how the nonnucleoside inhibitors of the HIV reverse transcriptase are different than the nucleoside inhibitors?


A) The nonnucleoside inhibitors prevent addition of the next nucleotide.
B) The nonnucleoside inhibitors do not bind to the active site of the enzyme.
C) The nonnucleoside inhibitors must be activated by the cellular thymidine kinase.
D) The nonnucleoside inhibitors prevent synthesis of the reverse transcriptase.
E) The nonnucleoside inhibitors lack a 3' OH group.

Answer

B