How does the antiviral drug amantadine inhibit the replication of influenza?

A) It binds to the M2 ion channel and blocks the uncoating of the RNPs.
B) It binds to sialic acid on the host cell and prevents binding of the virion.
C) It binds to the HA protein on the virion and prevents binding to the host cell.
D) It binds to the polymerase protein and halts genome replication.
E) It binds to the nucleocapsid protein and prevents packaging of the viral RNA.