The 10,000 origins of replication in mammalian cells suggests that there is
A)at least one origin of replication per loop of DNA. B)probably one origin of replication every other loop of DNA C)a random distribution of origins of replication across the genome. D)an even distribution of origins of replication across the genome.
In a typical human cell, DNA polymerase synthesizes DNA at a rate of approximately 50 nucleotides per second.Human chromosome 1 contains about 250 million base pairs.If a single origin of replication were used, how long would it take the cell to copy this chromosome?
A)less than 24 hours B)1 to 2 days C)1 to 2 weeks D)50 to 60 days E)110 to 120 days
Telomeres have at least two roles in chromosome integrity.Telomeres are composed of repeat sequences homologous to the RNA in telomerase used to replicate chromosome ends.Second, they
A)allow the chromosome to shorten each generation to speed up replication. B)interact with shelterin complexes that protect chromosome ends from degradation. C)permit the hairpin turn at the end to be cleaved. D)carry genes needed for DNA replication.