All of the Following are True of the R Point

Question

All of the following are true of the R point EXCEPT
A)It occurs at the G2/M transition.
B)The cell's fate at this point may be influenced by growth factors in the cell's surroundings.
C)Deregulation of signaling controlling the R point is common in cancer cells.
D)It is followed by the activation of cyclin E/CDK2 complexes.
E)Passage through this point is regulated by phosphorylation of pRb.

Accepted Answer

The R point occurs at the G1/S transition, not at the "G₂/M transition," which appears to be a typographical or nonsensical error. The correct aspects of the R point include its regulation by growth factors, its deregulation in cancer, the activation of cyclin E/CDK2 complexes following it, and its regulation through the phosphorylation of pRb.