Course

Introductory Biology

Study Pack

Set 17 From Gene To Protein

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Question 1

(Multiple Choice)

Free
Which of the following is a function of a poly-A signal sequence?

A) It adds the poly-A tail to the 3' end of the mRNA.
B) It codes for a sequence in eukaryotic transcripts that signals enzymatic cleavage ~10-35 nucleotides away.
C) It allows the 3' end of the mRNA to attach to the ribosome.
D) It is a sequence that codes for the hydrolysis of the RNA polymerase.
E) It adds a 7-methylguanosine cap to the 3' end of the mRNA.

Answer

Question 2

(Multiple Choice)

Free
Which of the following variations on translation would be most disadvantageous for a cell?

A) translating polypeptides directly from DNA
B) using fewer kinds of tRNA
C) having only one stop codon
D) lengthening the half-life of mRNA
E) having a second codon (besides AUG) as a start codon

Answer

Question 3

(Multiple Choice)

Free
Garrod's information about the enzyme alteration resulting in alkaptonuria led to further elucidation of the same pathway in humans. Phenylketonuria (PKU)occurs when another enzyme in the pathway is altered or missing, resulting in a failure of phenylalanine (phe)to be metabolized to another amino acid: tyrosine. Tyrosine is an earlier substrate in the pathway altered in alkaptonuria. How might PKU affect the presence or absence of alkaptonuria?

A) It would have no effect, because PKU occurs several steps away in the pathway.
B) It would have no effect, because tyrosine is also available from the diet.
C) Anyone with PKU must also have alkaptonuria.
D) Anyone with PKU is born with a predisposition to later alkaptonuria.
E) Anyone with PKU has mild symptoms of alkaptonuria.

Answer