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Genetics

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Set 19 Epigenetic Regulation In Eukaryotes

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Question 1

(Multiple Choice)

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In terms of overall methylation,what is the most accurate way to describe the genomes of cancer cells?

A)A few types of cancers are have hypomethylated genomes,but it is not common in most types of cancers.
B)Cancer cells have an overall hypermethylated genome compared to healthy cells.
C)A few types of cancers are have hypermethylated genomes,but it is not common in most types of cancers.
D)Cancer cells have equivalent methylated genomes compared to healthy cells.
E)Cancer cells have an overall hypomethylated genome compared to healthy cells.

Answer

Question 2

(Multiple Choice)

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Different modification of the histone have different effects on gene expression.For instance,the ninth amino acid of histone 3 is a lysine H3K9)can be acetylated once or methylated up to three times.Which of the following is true regarding H3K9 modification?

A)If H3K9 has two methyl groups,then the gene will be activated.
B)If H3K9 has three methyl groups,then the gene will be repressed.
C)If H3K9 is acetylated,then the gene will be repressed.
D)If H3K9 has three methyl groups,it is maximally activated compared to only having one methyl group.
E)If H3K9 has a single methyl group,then the gene will be repressed.

Answer

Question 3

(Multiple Choice)

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Long noncoding RNAs that partially overlap protein- coding genes and are transcribed in the opposite direction are best classified as________ .

A)bidirectional lncRNA genes
B)antisense lncRNA genes
C)microRNAs
D)piwi interacting RNAs
E)intronic lncRNA genes

Answer