St6 Advances In Neurogenetics The Study Of Huntington Disease - Concepts of Genetics | Biology+

Course

Genetics

Study Pack

Set 1: Introduction to Genetics

Set 2: Mitosis and Meiosis

Set 3: Mendelian Genetics

Set 4: Extensions of Mendelian Genetics

Set 5: Chromosome Mapping in Eukaryotes

Set 6: Genetic Analysis and Mapping in Bacteria and Bacteriophages

Set 7: Sex Determination and Sex Chromosomes

Set 8: Chromosome Mutations: Variation in Number and Arrangement

Set 9: Extranuclear Inheritance

Set 10: DNA Structure and Analysis

Set 11: DNA Replication and Recombination

Set 12: DNA Organization in Chromosomes

Set 13: The Genetic Code and Transcription

Set 14: Translation and Proteins

Set 15: Gene Mutation,dna Repair,and Transposition

Set 16: Regulation of Gene Expression in Bacteria

Set 17: Transcriptional Regulation in Eukaryotes

Set 18: Post-Transcriptional Regulation in Eukaryotes

Set 19: Epigenetic Regulation in Eukaryotes

Set 20: Recombinant Dna Technology

Set 21: Genomic Analysis

Set 22: Applications of Genetic Engineering and Biotechnology

Set 23: Developmental Genetics

Set 24: Cancer Genetics

Set 25: Quantitative Genetics and Multifactorial Traits

Set 26: Population and Evolutionary Genetics

Set 27: CRISPR and Genomic Editing

Set 28: DNA Forensics

Set 29: Genomics and Precision Medicine

Set 30: Genetically Modified Foods

Set 31: Gene Therapy

Set 32: Advances in Neurogenetics: The Study of Huntington Disease

St6 Advances In Neurogenetics The Study Of Huntington Disease

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St6 Advances In Neurogenetics The Study Of Huntington Disease

(Multiple Choice)

Free

Gene silencing has been effective in mouse models of HD that are heterozygous for the mHTT gene.The results are promising as_______ .

A)the injection into both sides of the mouse brain resulted in reduced mHTT
B)the study demonstrated the ZFN only targeted the mHTT allele and left the normal HTT expression level unchanged
C)the injection into one side of the mouse brain affected both sides of the brain
D)both mHTT and HTT were down regulated

Answer

(Essay)

Free

Other neurodegenerative diseases also function through aggregation of misfolded proteins.However,the initial protein aggregates are different in each disease.Work on HD may still be vital to treating other diseases as_______
.
A)not all neurodegenerative disease spread
B)the method of disaggregation is similar in all neurodegenerative disease
C)other neurodegenerative diseases use axonal transport to spread to unaffected cells
D)the method of aggregation is the same in all neurodegenerative disease

Answer

(Essay)

Free

Explain how the use of sequencing technologies finally brought the search for the HD gene to a close as reported by the Huntington's Disease Collaborative Research Group.

Answer

Sequencing of the contigs that covered t...

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