A)A chromosome deletion has removed a tumor-suppressor gene.
B)A chromosome deletion has removed an oncogene.
C)There is a chromosome duplication that involves a segment with an oncogene.
D)A translocation has brought the MYC gene next to a different regulatory region.
E)The MYC gene has been amplified.

A)the observation that certain tumor-suppressor genes and oncogenes are involved in a sequential manner in the development of colon cancer.
B)the fact that proto-oncogenes are widely conserved in evolution.
C)the usual occurrence of retinoblastoma at a young age.
D)the development of a cancer as a result of activation of a single oncogene by any of a variety of mechanisms.
E)the fact that there are many genetic and epigenetic mechanisms that lead to inactivation of the same tumor-suppressor gene.

A)Proto-oncogenes
B)Tumor-suppressor genes
C)Passenger genes
D)Inhibitor genes
E)Driver genes