Course

Biochemistry

Study Pack

Set 31 Post Transcriptional Regulation Of Gene Expression

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Question 1

(Multiple Choice)

Free
Synthesized mRNAs containing mutations could potentially lead to the synthesis of toxic proteins.Which of the following mechanisms eliminates these mRNAs?

A)by nonsense-mediated decay (NMD)
B)by stabilizing RNA-binding proteins (RBPs)
C)by AU-rich elements
D)by premature termination codons (PTCs)

Answer

Question 2

(Multiple Choice)

Free
Which of the following AUBPs is known to function by out-competing other AUBPs for binding to AREs?

A)TTP
B)AUF-1
C)KSRP
D)HuR

Answer

Question 3

(Multiple Choice)

Free
Which of the following is a part of the eukaryotic deadenylation process?

A)adenylation of circularized mRNA
B)an increase in binding sites for PABP
C)mRNA linearization once the poly(A)tail is down to approximately 80 nucleotides
D)decreased interaction between PABP and eIF4G

Answer