In patients with Parkinson's disease, neurons in the SNc die. Based on the basic circuitry in Figure Q11-13, why does the absence of these neurons result in excessive activation of the inhibitory output neurons in the GPi/SNr? Figure Q11-13

Question

In patients with Parkinson's disease, neurons in the SNc die. Based on the basic circuitry in Figure Q11-13, why does the absence of these neurons result in excessive activation of the inhibitory output neurons in the GPi/SNr?

Figure Q11-13