Which is NOT an Example of a Disease Involving Prions

Question

Which is NOT an example of a disease involving prions? Select all that apply.
A) Kuru
B) Creutzfeldt-Jakob disease
C) Scrapie
D) Huntington's disease
E) Amyotrophic lateral sclerosis

Accepted Answer

Huntington's disease and Amyotrophic lateral sclerosis (ALS) are not caused by prions. Huntington's disease is a genetic disorder caused by a mutation in the HTT gene, while ALS, also known as Lou Gehrig's disease, is a neurodegenerative disease with causes that are not fully understood but are not related to prion proteins. Prions are misfolded proteins that cause diseases like Kuru, Creutzfeldt-Jakob disease, and Scrapie by inducing normal proteins in the brain to misfold.