Question 7

(Multiple Choice)

The function of the eukaryotic DNA replication factor PCNA (proliferating cell nuclear antigen) is similar to that of the β\beta subunit of bacterial DNA polymerase III in that it:


A) facilitates replication of telomeres.
B) forms a circular sliding clamp to increase the processivity of replication.
C) has a 3ʹ \rightarrow 5ʹ proofreading activity.
D) increases the speed but not the processivity of the replication complex.
E) participates in DNA repair.

Answer