The Anti-Influenza Drug Amantadine Blocks Entry of the Virion by Raising

Question

The anti-influenza drug amantadine blocks entry of the virion by raising the pH of the endosome.

Accepted Answer

Amantadine blocks the M2 ion channel in the influenza A virus, which prevents the uncoating process of the virus by keeping the pH of the endosome low, not by raising it.