What is the Definition of a Therapeutic Index When Discussing

Question

What is the definition of a therapeutic index when discussing an antiviral drug?
A) The amount of the drug that inhibits the virus replication.
B) The amount of the drug that is toxic to the host cell.
C) The amount of the drug that is inhibits viral replication divided by the amount of the drug that is toxic.
D) The dose that exerts 50% toxic effect divided by the does that exerts a 50% antiviral effect.
E) The amount of the drug that kills 50% of the hosts.

Accepted Answer

The therapeutic index is a ratio that compares the toxic dose to the effective dose of a drug, specifically the dose that causes a 50% toxic effect to the dose that achieves a 50% antiviral effect.