Why is it unlikely that there will ever be an effective vaccine against the rhinovirus, the major cause of the common cold?

A) The immune system is not very effective at attacking rhinoviruses.
B) There are over 100 different serotypes of rhinovirus.
C) The immune system does not protect the nose.
D) The common cold is too fast for the immune system to fight off.
E) Antibodies can not bind to the rhinovirus virion very well.