Which of the Following Types of Mutations are MOST Likely

Question

Which of the following types of mutations are MOST likely to be found in cancer cells?
A)Activating mutations in pRb
B)Mutations resulting in deregulation of the restriction point
C)Mutations resulting in enhanced restriction point regulation
D)Mutations that promote differentiation
E)C and D

Accepted Answer

Mutations resulting in deregulation of the restriction point are most likely to be found in cancer cells. This is because cancer cells need to constantly grow and divide without being regulated by external signals, and the restriction point is a key control point in cell cycle regulation. Mutations that result in enhanced restriction point regulation or promote differentiation would actually inhibit cancer development. Activating mutations in pRb are also important in cancer development, but they are not the most likely type of mutation to be found in all cancer cells.