A)occurred during the late 1800s to early 1900s.
B)started in the 1990s with the advent of genetic engineering.
C)is a time when the knowledge of and techniques to work with bacteria blossomed.
D)was when people realized that diseases could be caused by invisible agents.
E)occurred during the late 1800s to early 1900s, is a time when the knowledge of and techniques to work with bacteria blossomed AND was when people realized that diseases could be caused by invisible agents.