A) a region of the enzyme other than the active site.
B) the active site.
C) the substrate.
D) the product.
E) the surrounding tissue.

A) there are large changes in the net free energy from substrate to product.
B) there are small changes in the net free energy from substrate to product.
C) there is no change in the net free energy from substrate to product.
D) a reaction between products is unlikely due to the high activation energy.

A) vitamins.
B) isoenzymes.
C) coenzymes.
D) modulators.