How Do Germ-Line Mutations Differ from Somatic Mutations

Question

How do germ-line mutations differ from somatic mutations?
A)Germ-line mutations involve small changes to DNA such as base-pair substitutions, while somatic mutations usually involve large deletions.
B)Germ-line mutations occur during DNA replication, while somatic mutations do not.
C)Germ-line mutations result in mutant gametes, while somatic mutations do not.
D)Germ-line mutations are reversible, while somatic mutations are not.
E)Germ-line mutations result in cancers, while somatic mutations do not.

Accepted Answer

Germ-line mutations occur in the germ cells that give rise to sperm and egg cells, leading to the transmission of the mutation to offspring. Somatic mutations occur in non-germ cells and do not affect the germ cells, so they are not passed on to offspring.