Synthesizes the Lagging Strand of the DNA

Question

Synthesizes the lagging strand of the DNA.
A) DNA ligase
B) DNA primase
C) Topoisomerase
D) DNA polymerase I
E) DNA polymerase III

Accepted Answer

DNA polymerase III is the enzyme responsible for synthesizing the lagging strand of DNA during replication. It works in conjunction with DNA primase to make short RNA primers which are then elongated by DNA polymerase III. DNA polymerase I is responsible for removing the RNA primers and replacing them with DNA, while DNA ligase joins the Okazaki fragments together. Topoisomerase helps to relieve tension in the double-stranded DNA molecule during the replication process, but it is not directly involved in synthesizing the lagging strand.