The Folded Conformation of Proteins Can Be Stabilized by the Binding

Question

The folded conformation of proteins can be stabilized by the binding of a metal ion or cofactor.

Accepted Answer

Metal ions or cofactors can form strong interactions with amino acid residues in the protein, helping to stabilize the folded structure. Examples include the heme group in hemoglobin and iron-sulfur clusters in certain enzymes.