Question 1

(Multiple Choice)

The two step reaction catalyzed by isocitrate dehydrogenase involves:
A.β-decarboxylation expelling the α-keto carboxyl as CO2.
B.oxidation of the C-2 alcohol of isocitrate to form oxalosuccinatE.
C.oxidation of the C-2 alcohol to form oxaloacetatE.
D.β-elimination expelling the central carboxyl group as CO2.


A) A and B
B) B and C
C) C and D
D) A and C
E) B and D

Answer

E