Which of the Following is the Regulatory Step in Cholesterol

Question

Which of the following is the regulatory step in cholesterol synthesis?
A)HMG-CoA synthase
B)HMG-CoA lyase
C)HMG-CoA reductase
D)squalene synthase
E)squalene epoxidase

Accepted Answer

HMG-CoA reductase is the regulatory step in cholesterol synthesis as it converts HMG-CoA to mevalonate, which is a precursor for cholesterol synthesis. The activity of this enzyme is tightly regulated by feedback inhibition, transcriptional control, and post-translational modification.