What is the Function of the VA RNAs Produced by Adenovirus

Question

What is the function of the VA RNAs produced by adenovirus?
A) Inhibition of the cellular RNA polymerase III.
B) Inhibition of the interferon induced PKR kinase.
C) Stimulation of translation of viral mRNAs.
D) Regulation of mRNA stability.
E) Inhibition of the adaptive immune system.

Accepted Answer

The VA RNAs produced by adenovirus act as inhibitors of the interferon-induced protein kinase R (PKR), which is responsible for inhibiting protein synthesis in response to viral infection. By inhibiting PKR, the virus is able to continue translating its own mRNAs and replicating within the host cell without interference from the host's immune response.