What is a Genomic DNA Library

Question

What is a genomic DNA library?
A)a collection of short fragments from nuclear DNA digestion
B)a circular DNA molecule of 1 kb to 200 kb found in bacteria and yeast cells
C)a set of cloned fragments that collectively represent the genes of a particular organism
D)a short segment of DNA whose sequence is complementary to a portion of the DNA of interest

Accepted Answer

A genomic DNA library is a collection of cloned fragments of an organism's DNA that collectively represent its entire genome. This library is created by isolating and fragmenting the entire genomic DNA from an organism and inserting the fragments into a vector that can be propagated in a host organism, such as bacteria. The resulting library of clones can then be screened to identify and isolate genes of interest. Option A is incorrect because a genomic DNA library contains full-length DNA fragments and not short fragments. Option B describes a plasmid, which is not a genomic DNA library. Option D describes a DNA probe, which is used to identify a specific DNA sequence but is not a genomic DNA library.