Which of the Following is NOT an Allosteric Regulator of Phosphofructokinase-1

Question

Which of the following is NOT an allosteric regulator of phosphofructokinase-1?
A)glucose-6-phosphate
B)ATP
C)AMP
D)?-D-fructose-2,6-bisphosphate

Accepted Answer

Glucose-6-phosphate binds to the active site of phosphofructokinase-1 and acts as a substrate, not an allosteric regulator. On the other hand, ATP, AMP, and b-D-fructose-2,6-bisphosphate are allosteric regulators and bind to allosteric sites on the enzyme to regulate its activity.