Which of the Following is a Characteristic of Phosphofructokinase-1 (PFK-1)

Question

Which of the following is a characteristic of phosphofructokinase-1 (PFK-1)?
A)ATP increases the affinity of the enzyme for fructose-6-phosphate.
B)It is the most important regulatory site in glycolysis.
C)PFK-1 activity is a function of the lipid content of the cell.
D)ATP decreases the Kmof PFK-1 for fructose-6-phosphate.

Accepted Answer

PFK-1 is the most important regulatory site in glycolysis. A and D are incorrect because ATP actually inhibits PFK-1 activity and increases the KM for fructose-6-phosphate. C is also incorrect as PFK-1 activity is not related to the lipid content of the cell.