Which of the following concerning the isomerase reaction of glucose-6-phosphate to fructose-6-phosphate is correct?

A)Zn²⁺ is required for activity.
B)It is a ketose-to-aldose isomerization.
C)Transferring the carbonyl from C-1 to C-2 creates a new primary alcohol group at C-1.
D)The reaction is irreversible with a large negative ∆G.