Which of the following is NOT an important reason to phosphorylate glucose in the first step of glycolysis?

A)The large positive free energy is important in getting the pathway started.
B)Glucose-6-phosphate has a negative charge,preventing transport out of the cell.
C)The concentration of free glucose in the cell is lowered,favouring influx of glucose.
D)Regulatory control can be imposed only at a reaction,not at equilibrium.