Which of the following regarding the hydrolysis of p-nitrophenyl acetate by chymotrypsin is correct?
A)The active site contains a serine residue,an unprotonated histidine,and an unprotonated aspartate residue at pH 7.0 prior to binding the substrate. B)The first product is acetic acid. C)An actyl-enzyme tetrahedral intermediate forms during the mechanism. D)Attack of a water molecule on the acyl-enzyme intermediate yields the first product.