Which of the Following Best Describes Electrophoretic Gels Used for DNA

Question

Which of the following best describes electrophoretic gels used for DNA?
A) Most separations are done horizontally, while sequencing gels are typically run vertically.
B) Most separations are done vertically, while sequencing gels are typically run horizontally.
C) Most electrophoretic gels are run horizontally, whether for separation or sequencing.
D) Most electrophoretic gels are run vertically, whether for separation or sequencing.

Accepted Answer

Electrophoretic gels for DNA separation, such as agarose gels, are typically run horizontally due to their setup and the nature of the gel matrix. However, DNA sequencing gels, which are often polyacrylamide gels, are run vertically because this setup allows for better resolution necessary for reading the sequence.