In Its Non-Phosphorylated State Cofilin Can Sever Actin Filaments

Question

In its non-phosphorylated state cofilin can sever actin filaments.

Accepted Answer

Cofilin is an actin-binding protein that can bind to and sever actin filaments in its non-phosphorylated state. When cofilin is phosphorylated, it loses its ability to bind to actin and sever filaments.