Which of the Following is a Function of a Poly-A

Question

Which of the following is a function of a poly-A signal sequence?
A)It adds the poly-A tail to the 3' end of the mRNA.
B)It codes for a sequence in eukaryotic transcripts that signals enzymatic cleavage ~10-35 nucleotides away.
C)It allows the 3' end of the mRNA to attach to the ribosome.
D)It is a sequence that codes for the hydrolysis of the RNA polymerase.
E)It adds a 7-methylguanosine cap to the 3' end of the mRNA.

Accepted Answer

The poly-A signal sequence is a sequence in eukaryotic transcripts that signals enzymatic cleavage ~10-35 nucleotides away from the sequence, resulting in the addition of a poly-A tail to the 3' end of the mRNA. This poly-A tail is important for stability and translation of the mRNA.