Which of the Following Variations on Translation Would Be Most

Question

Which of the following variations on translation would be most disadvantageous for a cell?
A)translating polypeptides directly from DNA
B)using fewer kinds of tRNA
C)having only one stop codon
D)lengthening the half-life of mRNA
E)having a second codon (besides AUG)as a start codon

Accepted Answer

Translating polypeptides directly from DNA would be the most disadvantageous for a cell because it would not allow for any post-transcriptional modifications, such as splicing, capping, or tailing, to occur on the mRNA before translation. This would limit the cell's ability to fine-tune gene expression and also increase the likelihood of errors in translation.