Question 24

(Multiple Choice)

The transcription regulator AIRE (autoimmune regulator) plays a key role in developing immunological self-tolerance by promoting the production of various cellular proteins that are mainly expressed outside the thymus. Which of the following cells have the highest level of AIRE?


A) Double-negative thymocytes
B) Double-positive thymocytes
C) Lymphoid follicle cells in lymph nodes
D) Thymus epithelial cells
E) Peyer's patch cells

Answer