Indicate whether each of the following descriptions better applies to the clonal anergy (A), clonal deletion (D), receptor editing (E), or clonal suppression (S) mechanism of immunological self-tolerance. Your answer would be a five-letter string composed of letters A, D, E, and S only, e.g. SADSS.
( ) It involves apoptosis of self-reactive cells.
( ) It is mostly limited to B cells.
( ) It involves regulatory T (T??g) cells.
( ) It involves DNA recombination.
( ) It is limited to central tolerance processes.