Question 53

(Short Answer)

Indicate true (T) and false (F) statements below regarding the mTOR complexes. Your answer would be a four-letter string composed of letters T and F only, e.g. TTTF.
( ) mTOR in complex 1 contains the protein raptor, is sensitive to rapamycin, and stimulates cell growth.
( ) Akt activation is stimulated by mTOR in complex 2, which contains the protein rictor.
( ) Akt activates mTOR in complex 2 by activating a Rheb-GAP called Tsc2.
( ) mTOR in complex 1 is activated in the presence of growth factors.

Answer


mTOR complex 1 is rapamycin-sensitive,...

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