Question 39

(Short Answer)

Indicate whether the C-terminus (C) or the N-terminus (N) of each of the following proteins is expected to be located in the cytosol upon membrane integration of the protein. Your answer would be a three-letter string composed of letters C and N only, e.g. CCC.
( ) A single-pass transmembrane protein that has one N-terminal signal sequence and one internal stop-transfer signal
( ) A single-pass transmembrane protein that has one internal signal sequence that is preceded by a patch of positively charged residues
( ) An ER tail-anchored protein

Answer


In the first case, the N-terminal sign...

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