Indicate whether each of the following manipulations or procedures used in current recombinant DNA technology commonly rely on an enzyme (E) or are done nonenzymatically (N). Your answer would be a six-letter string composed of letters E and N only, e.g. EEEEEE.
( ) Cleavage of DNA at specific sites
( ) DNA ligation
( ) DNA cloning
( ) Nucleic acid hybridization
( ) Synthesis of DNA of any desired specific sequence
( ) DNA sequencing