Indicate whether each of the following descriptions better matches the major histones (M) or the histone variants (V). Your answer would be a six-letter string composed of letters M and V only, e.g. VVMVMV.
( ) They are more highly conserved over long evolutionary time scales.
( ) They are present in much smaller amounts in the cell.
( ) They are synthesized primarily during the S phase of the cell cycle.
( ) Their incorporation often requires histone exchange.
( ) They are often inserted into already-formed chromatin.
( ) They are assembled into nucleosomes just behind the replication fork.