Which of the Following is True of Chemokines

Question

Which of the following is true of chemokines?
A) They ensure production of enough leukocytes.
B) They are involved in B lymphocyte activation and differentiation.
C) They are chemotactic factors for leukocytes.
D) They cause basophils and eosinophils to degranulate.
E) They are substances used to signal between leukocytes.

Accepted Answer

Chemokines are chemotactic factors that signal leukocytes to migrate towards a site of inflammation or infection. They do not ensure production of leukocytes or directly play a role in B lymphocyte activation and differentiation. While they may attract basophils and eosinophils to a site, they do not cause degranulation. They are used to signal between leukocytes in the process of chemotaxis.