Oxidative Catabolism of Benzoate and Other Aromatic Compounds is Catalyzed

Question

Oxidative catabolism of benzoate and other aromatic compounds is catalyzed by
A) 2-oxoglutarate:NADPH oxidoreductase.
B) benzoyl-S-CoA reductase.
C) specific dioxygenases.
D) NADPH:ferredoxin oxidoreductase.
E) catechol 2,3, monooxygenase.

Accepted Answer

The oxidative catabolism of benzoate and other aromatic compounds is primarily catalyzed by specific dioxygenases. These enzymes introduce molecular oxygen into the aromatic ring, leading to the formation of dihydroxyaromatic compounds that can be further metabolized by other enzymes. Other enzymes listed, such as NADPH:ferredoxin oxidoreductase and catechol 2,3, monooxygenase, may play a role in microbial metabolism, but they are not directly involved in the oxidative catabolism of aromatic compounds.