Question 98

(Multiple Choice)

Use the following information as background for the next few questions.
Immunodeficiencies can be genetic in origin, and two examples are Bruton's agammaglobulinemia, an X-linked disorder, and DiGeorge syndrome, caused by a deletion from chromosome 22. Bruton's disorder results in underdeveloped B cells, whereas DiGeorge syndrome results in a missing or seriously underdeveloped thymus.
-Bruton's disorder will likely include


A) the failure of heavy-chain gene rearrangement in B cells.
B) the failure to incorporate CD4 receptors into cell membranes.
C) an underexpression of the gene for the β chain of the T cell receptor.
D) an underexpression of the gene for the CD8 receptor molecule.
E) the inability of the bone marrow cells to interact with MHC molecules.

Answer