"Ca₂+ Sen Sitization" in S M Ooth M Usc Le

Question

"Ca2+ sen sitization" in s m ooth m usc le refe rs to
A) The ability of Ca2+ to act ivate MLCK
B) Production of force at lower than normal levels of cytoplasmic [Ca2+]
C) Ca2+ activat ion of MLCP
D) Reduction in cytoplasmic [Ca2+] by phosphorylation of phospholamban
E) None of the above

Accepted Answer

Sensitization in smooth muscle refers to the muscle's ability to produce force at lower than normal levels of cytoplasmic calcium concentration ([Ca2+]). This means the muscle becomes more sensitive to calcium, allowing it to contract more easily without the need for increased calcium levels.